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Can you use vitamin C with AHAs or BHA?

Yes, with care

You can, but layering them increases the chance of stinging. Most people do better with vitamin C in the morning and exfoliating acids at night.

Why

A common claim is that acids 'deactivate' vitamin C. In fact, pure vitamin C serums are already very acidic, because L-ascorbic acid is absorbed best below about pH 3.5 (Pinnell 2001). The real issue is irritation: two acidic products in a row can leave skin red and tight.

Exfoliating acids also raise sun sensitivity, so daily sunscreen matters whichever way you use them.

How to use them

  • Morning: vitamin C, then moisturiser and SPF. Evening: AHA or BHA a few times a week.
  • With sensitive skin, choose a gentler vitamin C derivative and a milder acid such as lactic or mandelic acid.
  • Stop and give your skin a break if it feels hot, tight or looks shiny and red.

Read more about each ingredient

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Other combinations

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Sources

  1. Pinnell SR et al. Topical L-ascorbic acid: percutaneous absorption studies. Dermatol Surg, 2001.

Last reviewed 20 Oct 2026.

This is educational information, not medical advice. Introduce one new active at a time and patch test. If you use prescription skincare, or are pregnant or breastfeeding, check with your GP, pharmacist or dermatologist first.